Introduction: Recently, the effects of exercise on CNS have been extensively investigated, exercise has been proved to enhance cognitive functions such as learning and memory. For examples, exercise could induce positive change of brain structure, increase of GIAL cell generation and increase of neurosis. Especially, it has recently been considered that the increase of neurotrophins, which promote neurogenesis, plays an important role in the mechanism of the maintenance and improvement of brain cognitive function by exercise. The purpose of the present research to investigate the effects of FIET on serum levels of BDNF and GDNF and cognitive function.
Methodology: seven adolescent foottsal players (age 16.21± 0.39, height 170 ± 4.19 cm, body mass 67.38 ± 5.34 kg, VO2max 51.47± 6.9) underwent FIET. The FIET consisted of 45m shuttle runs (3×15m) with a progressive increased speed through recorded beeps. Between each running bouts, the players have a 10s active rest and 30s passive recovery for each FIET level. Blood samples were collected at four times: before, after1 and 2 level of FIET and in fatigue for the analysis of serum BDNF and GDNF. For the measurements of cognitive function, the In congruent S troop color word-test 12 option was performed at blood collecting times.
Results: Our results showed a similar pattern for BDNF and GDNF secretions in response to FIET. Both increasing during the first and second phase of FIET test and decreasing during the fatigue phase. However, only BDNF levels increased significantly from baseline to second level of FIET and decreased significantly during fatigue phase compared with Second level of FIET (P˂0.05). Error rate in the stroop test, decreased during the first and second phase of FIET and increased during the fatigue phase compared with baseline, but there was no significant change.
Discussion: In general, based on the stroop color-word test, seems to increase or decrease the BDNF and GDNF by FIET, and also exerts positive or negative effects on cognitive function.