Introduction: The oxidant-antioxidant imbalance, or oxidation stress, including biochemical adverse changes in diabetic conditions. The purpose of present study was to investigate the effect of 6 weeks of aerobic training and Corm (Pistacia Atlantica) extraction on total antioxidant capacity and Malondialdehyde levels in plasma and liver of streptococci-induced diabetic rats.
Methodology: 36 rats weighing 240-180 g were randomly assigned to the 5 groups. The exercise protocol included 6 weeks of aerobic exercise on a treadmill in three steps. Firstly, the rats walked on a treadmill with a slope of zero for one week at 5 to 10 meters per minute, for 10 minutes. In the second phase, that lasting three weeks, speed and duration of exercise sessions gradually increased to the amount specified, the speed of 20 meters per minute, the slope of 5% for 40 minutes. In the second phase, activity for 2 weeks at 20 meters per minute, the slope of 5% and continued for 40 minutes. Also, after each practice session, 25 mg per kg body weight of extraction was administered to rats. After 6 weeks, measured by the indices of malondialdehyde (MDA) and total antioxidant capacity (TAC) was done.
Results: The results showed that there is a significant difference between the groups in plasma total antioxidant capacity (P=0.006) and the levels of plasma Malondialdehyde (P=0.0001). On the other hand, analysis of variance showed that there wasnt a significant difference between different groups in the mean values of total antioxidant capacity and malondialdehyde of the liver (respectively; P=0.26, P=0.36).
Discussion: Results show that both exercise and baneh extraction affects on MDA and TAC in plasma. But does not affect the measured values in the liver.